Adriamycin induced pulseless electrical activity and cardiovascular collapse during general anesthesia for ventriculo-peritoneal shunt insertion. A case report

We report a case of a 45-year-old female undergoing an emergency ventriculoperitoneal shunt surgery. The patient had brain metastatic lesions of breast carcinoma with associated hydrocephalus. She had received Adriamycin as a part of chemotherapy regimen for breast cancer. Her preoperative cardiovas...

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Bibliographic Details
Published inMiddle East journal of anaesthesiology Vol. 19; no. 4; p. 841
Main Authors Chander, Bala, Bhagat, Hemant, Prabhakar, Hemanshu
Format Journal Article
LanguageEnglish
Published Lebanon 01.02.2008
Subjects
Anesthesia, General
Antibiotics, Antineoplastic - adverse effects
Brain Neoplasms - complications
Brain Neoplasms - secondary
Breast Neoplasms - drug therapy
Breast Neoplasms - pathology
Doxorubicin - adverse effects
Electroencephalography
Fatal Outcome
Female
Humans
Hydrocephalus - etiology
Hydrocephalus - surgery
Intraoperative Complications - chemically induced
Intraoperative Complications - physiopathology
Intraoperative Complications - therapy
Middle Aged
Pulse
Shock - chemically induced
Shock - physiopathology
Shock - therapy
Ventriculoperitoneal Shunt
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Summary:We report a case of a 45-year-old female undergoing an emergency ventriculoperitoneal shunt surgery. The patient had brain metastatic lesions of breast carcinoma with associated hydrocephalus. She had received Adriamycin as a part of chemotherapy regimen for breast cancer. Her preoperative cardiovascular status was normal. Under general anesthesia, the patient had a sudden cardiovascular collapse. The patient had a pulseless electrical activity and required inotropic support for cardiovascular stability. The possible cause is discussed.
ISSN:0544-0440