Cognitive development of normal school age children: a resting-state fMRI study
To investigate the characteristics of cognitive development in elementary school children using rest-fMRI methods. Twenty-nine normal school children were divided into three groups according to their ages (8, 10 & 12 years old) and received the resting-state fMRI scans. A regional homogeneity (R...
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Published in | Zhong hua yi xue za zhi Vol. 89; no. 19; p. 1313 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | Chinese |
Published |
China
19.05.2009
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Subjects | |
Online Access | Get more information |
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Summary: | To investigate the characteristics of cognitive development in elementary school children using rest-fMRI methods.
Twenty-nine normal school children were divided into three groups according to their ages (8, 10 & 12 years old) and received the resting-state fMRI scans. A regional homogeneity (ReHo) approach was used to analyze blood oxygen level-dependent fMRI (BOLD-fMRI) data in resting state. The fMRI data were processed with software SPM2 and REST 1.2.
Compared with younger groups (10 vs 8, 12 vs 10, 12 vs 8), the elder groups showed more increases in superior temporal gyrus (Z = 2.83, Z = 3.21), middle temporal gyrus (Z = 3.74, Z = 3.19, Z = 4.26), inferior temporal gyrus (Z = 3.01) and lentiform nucleus (Z = 3.31). In addition, the ReHo differences were demonstrated in superior frontal gyrus (Z = 3.21), middle frontal gyrus (Z = 3.19, Z = 3.22), medial frontal gyrus (Z = 3.15), lingual gyrus (Z = 3.43) and cerebellum (Z = 3.11, Z = 2.97) increased more in 12 years old group (12 vs 10, 12 vs 8). And the |
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ISSN: | 0376-2491 |
DOI: | 10.3760/cma.j.issn.0376-2491.2009.19.006 |