Impregnate occasion for male renal transplant recipients

To explore the impregnate occasion for male renal transplant recipients. Twenty-six male renal transplant recipients were divided into 3 groups according to the post-transplantation time and the administered dose of Cyclosporine A: 7 in Group A (less than 6 months after renal transplantation and at...

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Bibliographic Details
Published inZhonghua nan ke xue Vol. 14; no. 5; p. 448
Main Authors Xu, Long-Gen, Zhu, Xiao-Feng, Jin, Li-Ming, Xu, Hui-Ming, Ling, Xia, Tang, Xiao-Yang, Xu, Biao
Format Journal Article
LanguageChinese
Published China 01.05.2008
Subjects
Adult
Coitus
Cyclosporine - administration & dosage
Cyclosporine - therapeutic use
Dose-Response Relationship, Drug
Humans
Hydrogen-Ion Concentration
Immunosuppressive Agents - administration & dosage
Immunosuppressive Agents - therapeutic use
Kidney Transplantation
Male
Postoperative Period
Semen - chemistry
Semen - cytology
Semen - drug effects
Sperm Count
Sperm Motility - drug effects
Time Factors
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Summary:To explore the impregnate occasion for male renal transplant recipients. Twenty-six male renal transplant recipients were divided into 3 groups according to the post-transplantation time and the administered dose of Cyclosporine A: 7 in Group A (less than 6 months after renal transplantation and at the dose of 4.1-6 mg/[kg x d]), 11 in Group B (6-24 months and 2.1-4 mg/[kg x d]) and 8 in Group C (longer than 24 months and 1.3-2 mg/[kg x d]). The semen of the patients were detected and compared with those of 12 normal volunteers. Statistically significant differences were observed in sperm motility and sperm head deformity between Group A and C (P < 0.05), but not in pH value and sperm volume, vitality and concentration among the 3 groups (P > 0.05). For male renal transplant recipients, 2 years or longer after the transplantation is the most suitable time for impregnation.
ISSN:1009-3591