Assessment of the level of immunoglobulin E in patients with pyo-inflammatory diseases and its influence on the course of the infectious process

The level of immunoglobulin E (IgE) in patients with different pyo-inflammatory diseases was assessed and it was found to elevate in patients with acute appendicitis in 49% of cases, in patients with chronic relapsing furunculosis (CRF) in 41%, with chronic osteomyelitis--in 66.6%. In 8 out of 16 ex...

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Bibliographic Details
Published inVestnik hirurgii im. I.I. Grekova Vol. 167; no. 6; p. 40
Main Authors Druzhinina, T A, Molotilov, B A, Ivachev, A S, Peskov, A V, Levashova, O A, Titova, E V
Format Journal Article
LanguageRussian
Published Russia (Federation) 2008
Subjects
Acute Disease
Antibodies, Anti-Idiotypic - blood
Appendicitis - blood
Appendicitis - immunology
Biomarkers - blood
Chronic Disease
Disease Progression
Furunculosis - blood
Furunculosis - immunology
Humans
Immunoglobulin E - blood
Immunoglobulin E - immunology
Osteomyelitis - blood
Osteomyelitis - immunology
Recurrence
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Summary:The level of immunoglobulin E (IgE) in patients with different pyo-inflammatory diseases was assessed and it was found to elevate in patients with acute appendicitis in 49% of cases, in patients with chronic relapsing furunculosis (CRF) in 41%, with chronic osteomyelitis--in 66.6%. In 8 out of 16 examined patients with the elevated level of IgE there were antibodies to toxocars in titers 1:800, 1:400. No correlation with the IgE level was found in assessing the level of IL-4 and gamma-IFN in blood serum of patients with CRF. In patients with acute appendicitis, CRF and chronic osteomyelitis the elevated level of IgE can be considered as a marker of unfavorable course of pyo-inflammatory diseases. The elevated level of IgE does not influence the oxygen-dependent mechanisms of bactericidal action of neutrophils.
ISSN:0042-4625