Intestinal endotoxin in the pathogenesis of ocular inflammatory diseases and the antiendoxin constituent of its treatment

Blood was studied in 119 patients with ocular inflammatory lesions: endophthalmitis (n = 10), iridocyclitis of viral (n = 47) and unknown (n = 62) genesis, by using the procedures developed by the authors to determine the integral values of the concentration of endotoxin in systemic blood flow and t...

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Bibliographic Details
Published inPatologicheskaia fiziologiia i eksperimental'naia terapiia no. 1; p. 12
Main Authors Vyshegurov, Ia Kh, Anikhovskaia, I A, Batmanov, Iu E, Iakovlev, M Iu
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.01.2007
Subjects
Adult
Aged
Endophthalmitis - blood
Endophthalmitis - etiology
Endophthalmitis - therapy
Endotoxins - blood
Endotoxins - toxicity
Eye Infections - blood
Eye Infections - etiology
Eye Infections - therapy
Gentamicins - therapeutic use
Humans
Intestinal Diseases - microbiology
Iridocyclitis - blood
Iridocyclitis - etiology
Iridocyclitis - therapy
Lipopolysaccharides - blood
Luminol - analogs & derivatives
Middle Aged
Phthalazines - therapeutic use
Treatment Outcome
Uveitis - blood
Uveitis - etiology
Uveitis - therapy
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Summary:Blood was studied in 119 patients with ocular inflammatory lesions: endophthalmitis (n = 10), iridocyclitis of viral (n = 47) and unknown (n = 62) genesis, by using the procedures developed by the authors to determine the integral values of the concentration of endotoxin in systemic blood flow and the activity of antiendotoxin immunity. Intestinal endotoxin aggression was found to be involved in the pathogenesis of ocular inflammatory diseases. The use of drugs and procedures, which could diminish the entry of intestinal endotoxin into the blood stream and intensify the processes of its binding and release from systemic blood circulation, substantially enhanced the efficiency of a therapeutic process.
ISSN:0031-2991