Eosinophilic fasciitis in a 57-year-old Japanese-American woman

Eosinophilic fasciitis (EF) is a rare connective tissue disorder characterized by symmetrical sclerodermatous skin changes primarily affecting the extremities and histologically, by thickening of the fascia with chronic inflammatory infiltrate containing eosinophils. EF is associated with peripheral...

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Published inHawaii medical journal (1962) Vol. 66; no. 3; pp. 64 - 66
Main Authors Ambrocio, Deryll U, Uramoto, Kristine
Format Journal Article
LanguageEnglish
Published United States 01.03.2007
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Summary:Eosinophilic fasciitis (EF) is a rare connective tissue disorder characterized by symmetrical sclerodermatous skin changes primarily affecting the extremities and histologically, by thickening of the fascia with chronic inflammatory infiltrate containing eosinophils. EF is associated with peripheral eosinophilia, hypergammaglobulinemia, and an elevated ESR. Reported is a case of EF in a 57-year-old Japanese-American woman who refused treatment with prednisone, review of other treatment options, and discussion of key differences between this disease and scleroderma.
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ISSN:0017-8594