Screening of cytotoxic activity against B16 tumor cell of mangrove fungi isolate from Qinglan harbor in Hainan

Six hundred and eight fungi strains were isolated from seventy-eight samples of mangrove plants and soil that collected from Qinglan harbor. Cyctotoxic activity was detected by observing the growth inhibition or killing of the tumor cells under microscope. The result showed that 81 strains (about 13...

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Bibliographic Details
Published inShengwu gongcheng xuebao Vol. 24; no. 6; p. 975
Main Authors Miao, Chengdu, Zhuang, Ling, Lin, Haipeng, Hong, Kui
Format Journal Article
LanguageChinese
Published China 01.06.2008
Subjects
Animals
China
Cytotoxicity Tests, Immunologic
Fungi - isolation & purification
Fungi - physiology
Melanoma, Experimental - pathology
Mice
Plant Roots - microbiology
Rhizophoraceae - microbiology
Soil Microbiology
Tumor Cells, Cultured
China
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Summary:Six hundred and eight fungi strains were isolated from seventy-eight samples of mangrove plants and soil that collected from Qinglan harbor. Cyctotoxic activity was detected by observing the growth inhibition or killing of the tumor cells under microscope. The result showed that 81 strains (about 13.32% of the total strains isolated) displayed cytotoxic activity against B16 tumor cell. The most fungi strains were isolated from mangrove plant Sonneratia alba, and most of cytotoxic active fungi strains were isolated from mangrove plant Heritiera littoralis.
ISSN:1000-3061