Impact of progesterone in peritoneal fluid on sperm motility in infertile patients with endometriosis

• Published in: Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban Vol. 39; no. 3; p. 424
• Main Authors: Xu, Yan-Fei, Tan, Shi-Qiao, Luo, Li
• Format: Journal Article
• Language: Chinese
• Published: China 01.05.2008
• Subjects: Adult; Ascitic Fluid - metabolism; Endometriosis - complications; Female; Humans; Infertility, Female - etiology; Infertility, Female - metabolism; Infertility, Female - physiopathology; Male; Progesterone - metabolism; Progesterone - physiology; Sperm Motility - physiology; Young Adult
• ISSN: 1672-173X

To evaluate the impact of progesterone in the peritoneal fluid on human sperm motility in the infertile patients with endometriosis. Peritoneal fluids were collected from 41 patients by laparoscopy, of which 17 were infertile patients with endometriosis, 11 were fertile patients with endometriosis and 13 were fertile controls. The concentrations of progesterone in the peritoneal fluids were measured by the immulyze-enzyme amplified luminescence system. After 4 h of incubation in vitro with the collected peritoneal fluids, sperm motility was assessed by the computer-assisted analyzer (CASA). The concentrations of progesterone in the peritoneal fluids in the patients (infertile patients with endometriosis, fertile patients with endometriosis and the fertile controls) did not differ significantly (P > 0.05) in the proliferate phase. The sperms incubated with the peritoneal fluids from the patients with endometriosis had significant lower sperm motion parameters (A, VCL, VSL, VAP, ALH) than those of the fertile c