Study on detection of samples of Rh-weak D and Del

To study the detection of weak D and Del from samples initially screened RhD(-), RhD phenotype was initially screened by routine serological test, out of which weak D phenotype was detected by indirect antiglobulin test (IAT) and Del phenotype was detected by chloroform-trichloroethylene absorption-...

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Published inZhongguo shi yan xue ye xue za zhi Vol. 13; no. 3; p. 509
Main Authors Wang, Xiao-Zhu, Lan, Jiong-Cai, Wu, Xu-Hua, Zhou, Hua-You, Liu, Wei-Jia, Liu, Dan, Qi, Cun-Sheng, Zeng, Feng-Qin, Du, Ke-Qing
Format Journal Article
LanguageChinese
Published China 01.06.2005
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Summary:To study the detection of weak D and Del from samples initially screened RhD(-), RhD phenotype was initially screened by routine serological test, out of which weak D phenotype was detected by indirect antiglobulin test (IAT) and Del phenotype was detected by chloroform-trichloroethylene absorption-elution test. The results showed that 56 samples were RhD(-) confirmed by routine serology test, which were screened out of 26 200 donors, among them 5 samples were typed as weak D by IAT and 9 cases samples were typed as Del by absorption-elution test. In conclusion, the samples which typed as RhD(-) by routine serological test must be identified by IAT and chloroform-trchloroethylene absorption test is order to detect weak D and Del phenotype. It is important for clinical transfusion safely.
ISSN:1009-2137