A case of advanced hepatocellular carcinoma with tumor thrombus treated by transarterial chemoembolization therapy using cisplatin (CDDP) with DSM and SAP-MS

A 78-year-old woman with advanced HCC had been treated by transarterial chemoembolization with epirubicin, however, tumor progression was not controlled and a tumor thrombus was found in the portal vein trunk. A new treatment method for transarterial chemoembolization using CDDP with DSM and SAP-MS...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 32; no. 10; p. 1477
Main Authors Hori, Shinichi, Sugiura, Takashi, Shirai, Yasuhiro, Hiraishi, Kumiko
Format Journal Article
LanguageJapanese
Published Japan 01.10.2005
Subjects
Aged
Carcinoma, Hepatocellular - therapy
Chemoembolization, Therapeutic
Cisplatin - administration & dosage
Female
Hepatic Artery
Humans
Liver Neoplasms - therapy
Neoplastic Cells, Circulating - pathology
Polymers - administration & dosage
Portal Vein - pathology
Starch - administration & dosage
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Summary:A 78-year-old woman with advanced HCC had been treated by transarterial chemoembolization with epirubicin, however, tumor progression was not controlled and a tumor thrombus was found in the portal vein trunk. A new treatment method for transarterial chemoembolization using CDDP with DSM and SAP-MS was introduced. Marked regression of hepatic lesions and portal vein tumor thrombus was observed after two sessions. No adverse effect was found. The patient has been controlled without tumor recurrence and elevation of tumor marker for 14 months. A new treatment protocol will be useful for patients with far advanced hepatocellular carcinoma with portal vein tumor thrombus.
ISSN:0385-0684