Morphological observation on gastric mucosa membrane of patients with gastric ulcer treated with combined use of Qifang Weitong Powder and omeprazole

To observe the histological changes of gastric mucosa in patients with active gastric ulcer before and after treatment by Qifang Weitong Powder combined with omeprazole (QWP-Op). Sixty patients were equally randomized into the treated group and the control group. They were all treated in the 1st wee...

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Bibliographic Details
Published inZhongguo Zhong xi yi jie he za zhi Vol. 27; no. 7; p. 610
Main Authors Deng, Chang, Luo, Wei-sheng, Li, Gui-xian
Format Journal Article
LanguageChinese
Published China 01.07.2007
Subjects
Adult
Anti-Ulcer Agents - therapeutic use
Biopsy, Needle
Drug Therapy, Combination
Drugs, Chinese Herbal - therapeutic use
Female
Gastric Mucosa - pathology
Humans
Male
Middle Aged
Omeprazole - therapeutic use
Phytotherapy
Powders
Stomach Ulcer - drug therapy
Stomach Ulcer - pathology
Treatment Outcome
Young Adult
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Summary:To observe the histological changes of gastric mucosa in patients with active gastric ulcer before and after treatment by Qifang Weitong Powder combined with omeprazole (QWP-Op). Sixty patients were equally randomized into the treated group and the control group. They were all treated in the 1st week by the Helicobacter pylori eradication triad regimen. From the 2nd to 6th week, the study group re-ceived QWP-Op therapy, and the control group was given Omeprazole alone.Biopsy specimens were obtained around ulcer area before and after treatment for histological observation on changes of gastric mucosa membrane. The improvement of mucosal thickness and glandular morphology was better in the treated group than that in the control group (P <0.05). QWP-Op therapy can improve the histological quality of ulcer healing and restore the morphological structure of gastric mucosa in patients with active gastric ulcer.
ISSN:1003-5370