Extended transsphenoidal approach to giant tumors in sellar and clival area

To explore the effects of extended transsphenoidal approach, a new approach for removing giant tumors in sellar and clival area. Twenty-eight patients, 19 males and 9 females, aged 17 - 67 with a mean age of 47.8, with a mean history of 6.2 years, 13 with invasive giant pituitary adenoma, 10 with ch...

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Published inZhong hua yi xue za zhi Vol. 84; no. 20; p. 1693
Main Authors Wang, Ren-Zhi, Ren, Zu-Yuan, Su, Chang-Bao, Yang, Yi, Tao, Wei, Ma, Wen-Bin, Yin, Jian
Format Journal Article
LanguageChinese
Published China 17.10.2004
Subjects
Adenoma - surgery
Adolescent
Adult
Aged
Brain Neoplasms - surgery
Chordoma - surgery
Female
Humans
Hypophysectomy - methods
Male
Middle Aged
Pituitary Neoplasms - surgery
Sella Turcica
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Summary:To explore the effects of extended transsphenoidal approach, a new approach for removing giant tumors in sellar and clival area. Twenty-eight patients, 19 males and 9 females, aged 17 - 67 with a mean age of 47.8, with a mean history of 6.2 years, 13 with invasive giant pituitary adenoma, 10 with chordoma, 2 with giant cell tumor of bone, 2 with pituitary metastatic tumor, and 1 with pituitary endocrinal carcinoma underwent operation by extended transsphenoidal approach. The tumors were 3.0 - 5.5 cm in size. In 2 cases the tumor extended to the base of the frontal lobe, 7 tumors involved the cavernous sinus, and 19 extended to clivus. The tumor was totally removed in 19 patients, removed subtotally in 6 patients, and removed partially in 3 patients. Postoperative follow-up was performed for 6 months to 4 years. No recurrence occurred except for enlargement of 2 pituitary metastatic tumors and 1 chordoma. Extended transsphenoidal approach satisfactorily reaches and helps remove the giant tumors in sellar and c
ISSN:0376-2491