Radiofrequency ablation of liver metastasis from breast cancer

• Published in: Gan to kagaku ryoho Vol. 32; no. 11; p. 1676
• Main Authors: Seshimo, Akiyoshi, Kamio, Takako, Aratake, Kazuki, Ogawa, Shinpei, Oochi, Tetsuya, Aoyama, Kei, Itabashi, Michio, Shirotani, Noriyasu, Kameoka, Shingo
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.10.2005
• Subjects: Adult; Aged; Breast Neoplasms - pathology; Catheter Ablation; Combined Modality Therapy; Female; Humans; Liver Neoplasms - pathology; Liver Neoplasms - secondary; Liver Neoplasms - surgery
• ISSN: 0385-0684

As the hepatic metastasis from breast cancer has a tendency to have an extrahepatic lesion, systemic therapy therefore becomes acclimatization. However, local therapy is regarded as one of the choices if there is no extrahepatic lesion. We present three cases of liver metastasis from the breast treated by radiofrequency ablation (RFA). Case 1: A 65-year-old woman was treated by left mastectomy in 1997. Radiation exposure was performed for lung metastasis, and a weekly paclitaxel therapy was administered in 2001. We performed RFA percutaneously for liver metastasis of 2.8 cm in 2002. The aggravation spread to the lung lesion and she died after RFA within one year. The liver metastasis finally enlarged to 4 cm in size. Case 2: A 36-year-old woman was treated by left mastectomy (Stage IIIa), and was followed by chemotherapy in 2000. We performed RFA for metastasis of 2 cm of liver (S7) percutaneously in 2001, and didn't recognize a recurrence to date for 3 years and 8 months. Case 3: A 43-year-old woman was treated by left mastectomy (Stage IIIa), and followed by chemotherapy in 2003. We performed RFA for a liver metastasis of 3.5 x 4 cm under laparotomy in 2004. She has been disease free for 15 months.