Extended transsphenoidal operation for giant and invasive pituitary adenomas

To evaluate the possibility of extended transsphenoidal approach for removing the giant and invasive pituitary adenomas. The clinical data of 64 cases with giant and invasive pituitary adenoma treated by extended transsphenoidal approach were studied retrospectively. Among 64 patients, 51 had total...

Full description

Saved in:
Bibliographic Details
Published inChung-hua wai kʿo tsa chih Vol. 44; no. 22; p. 1548
Main Authors Wang, Ren-zhi, Yin, Jian, Su, Chang-bao, Ren, Zu-yuan, Yao, Yong, Tao, Wei
Format Journal Article
LanguageChinese
Published China 15.11.2006
Subjects
Adenoma - pathology
Adenoma - surgery
Adolescent
Adult
Aged
Female
Follow-Up Studies
Humans
Hypophysectomy - methods
Male
Microsurgery
Middle Aged
Neoplasm Invasiveness
Neuroendoscopy
Pituitary Neoplasms - pathology
Pituitary Neoplasms - surgery
Sphenoid Sinus - surgery
Treatment Outcome
Online AccessGet more information

Cover

More Information
Summary:To evaluate the possibility of extended transsphenoidal approach for removing the giant and invasive pituitary adenomas. The clinical data of 64 cases with giant and invasive pituitary adenoma treated by extended transsphenoidal approach were studied retrospectively. Among 64 patients, 51 had total resection and 13 had subtotal resection. 26 patients occurred transient diabetes insipidus, 5 patients with transient cerebrospinal rhinorrhoea and 1 patient occurred acute hypopituitarism postoperatively. There were no death or intracranial infection. After operation, 8 patients get radiotherapy, 6 patients receive medicine treatment. Postoperative follow-up period was 3 months to 6 years. No regrowth or recurrence was seen. The extended transsphenoidal approach has been proved to a safe and effective method to remove the giant and invasive pituitary adenomas. Patients who got subtotal resection need be close followed-up and receive radiotherapy or medicine treatment it necessary.
ISSN:0529-5815