Evaluation of Articles on Prognosis

People with a disease often have important questions about how their particular condition will affect their lives. Patients and their families want to know what to expect. Cohort studies recruit patients with a particular condition at baseline and follow them up to determine how well they fare over...

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Bibliographic Details
Published inPainless Evidence-Based Medicine pp. 74 - 86
Main Authors Tan, Nigel C.K, Uy, Elenore Judy B, Dans, Antonio L
Format Book Chapter
LanguageEnglish
Published United Kingdom John Wiley & Sons, Incorporated 2017
John Wiley & Sons, Ltd
Subjects
CLINICAL & INTERNAL MEDICINE
clinical prediction
derivation cohort
PEO
prognostic factors
randomized controlled trial
validation cohort
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Summary:People with a disease often have important questions about how their particular condition will affect their lives. Patients and their families want to know what to expect. Cohort studies recruit patients with a particular condition at baseline and follow them up to determine how well they fare over time. Cohorts that provide insight into prognosis may be found within other study designs. For example, the control group in a randomized controlled trial (RCT) may be regarded as a cohort from which information on prognosis may be derived. Appraisal of an article on prognosis begins with an evaluation of how well the study PEO addresses the clinician's own PEO. Validity can be appraised quickly by checking on the four criteria: due consideration of all important prognostic factors; objectivity of outcome assessment; completeness of follow‐up; and, in the case of prediction rules, an unbiased determination of the relative contributions of various prognostic factors.
ISBN:9781119196242
1119196248
DOI:10.1002/9781119196150.ch5