Chemoembolization in the treatment of metastatic ileocolic carcinoid

• Published in: Romanian journal of gastroenterology Vol. 11; no. 2; p. 141
• Main Authors: Diculescu, Mircea, Atanasiu, Călina, Arbănaş, Tudor, Croitoru, Adina, Mihalcea, Adela, Becheanu, Gabriel, Costinean, Stefan, Gheorghe, Liana, Capşa, Răzvan
• Format: Journal Article
• Language: English
• Published: Romania 01.06.2002
• Subjects: Carcinoid Tumor - diagnosis; Carcinoid Tumor - secondary; Carcinoid Tumor - therapy; Chemoembolization, Therapeutic; Colonic Neoplasms - pathology; Diagnosis, Differential; Humans; Ileal Neoplasms - pathology; Liver Neoplasms - secondary; Liver Neoplasms - therapy; Male; Middle Aged
• ISSN: 1221-4167

Carcinoid tumours are enigmatic, slow growing malignancies, which occur most frequently (74%) in the gastrointestinal tract. Symptoms of the carcinoid syndrome (flushing and diarrhoea) are infrequent, occurring in approximately 10% of the patients with small bowel carcinoid. A 45-year-old patient with multiple liver metastases, diagnosed in 1994 with nonHodgkin's lymphoma after undergoing surgery for a distal ileal tumour, was referred to us by the Department of Haematology. At that moment the issue of a differential diagnosis with a carcinoid tumour arose, due to the long evolution and lack of evidence to support the initial diagnosis. The carcinoid syndrome was in fact present (the patient experiencing flush after small amounts of alcohol and emotions) and also we identified elevated values of 5HIAA. Reevaluation of the histologic sections of the ileal tumour as well as an ultrasound guided fine needle aspiration of an intrahepatic lesion confirmed the diagnosis of "carcinoid tumour". This conclusion lead to new therapeutic options for this patient. One of the main therapeutic options used in treating multiple liver metastases from a carcinoid tumour is chemoembolization and this case offered an excellent opportunity to present this therapy.