Plasma levels of ascorbic acid and vitamin E in patients with liver cirrhosis

• Published in: Zhejiang da xue xue bao. Journal of Zhejiang University. Medical sciences. Yi xue ban Vol. 32; no. 6; pp. 533 - 535
• Main Authors: Lu, Xin-liang, Zhang, Zheng-liang, Zhou, Jun-fu, Cai, Jian-ting, Qian, Ke-da
• Format: Journal Article
• Language: Chinese
• Published: China 01.12.2003
• Subjects: Adult; Aged; Aged, 80 and over; Ascorbic Acid - blood; Female; Humans; Lipid Peroxides - blood; Liver Cirrhosis - blood; Liver Cirrhosis - metabolism; Male; Middle Aged; Vitamin E - blood
• ISSN: 1008-9292

To investigate the plasma levels of ascorbic acid and vitamin E in patients with liver cirrhosis and to explore their significance. The plasma levels of ascorbic acid,vitamin E and lipoperoxides in patients with liver cirrhosis were measured, and the results were compared with those of sex-and age-matched healthy subjects. The plasma levels of ascorbic acid, vitamin E and lipoperoxides in the patients group were (42.94 +/-6.99)micromol/L, (17.99 +/-3.51)micromol/L and (14.09 +/-1.28)micromol/L, respectively, while those in the control group were (53.30 +/-9.45)micromol/L (t=9.50, P=0.000), (24.59 +/-7.22)micromol/L (t=7.94, P=0.000) and (12.11 +/-1.20)micromol/L (t=17.21, P=0.000), respectively. The levels of ascorbic acid and vitamin E in patients with liver cirrhosis decrease significantly,which may indicates the disturbance of balance between oxidation and antioxidation.