FISH, cytogenetic analysis

We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-misma...

Full description

Saved in:
Bibliographic Details
Published inRinsho byori. The Japanese journal of clinical pathology Vol. Suppl 115; p. 30
Main Authors Miyanishi, S, Okumura, A
Format Journal Article
LanguageJapanese
Published Japan 01.03.2001
Subjects
Bone Marrow Transplantation
False Positive Reactions
Humans
In Situ Hybridization, Fluorescence - methods
Interferon-alpha - therapeutic use
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - diagnosis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy
Transplantation Chimera
Online AccessGet more information

Cover

More Information
Summary:We describe here the clinical applications of fluorescence in situ hybridization(FISH) in patients with chronic myelogenous leukemia under treatment with interferon-alpha, some cases with a false positive caused by preparation of specimen and/or probes, and the detection of chimerism after sex-mismatched bone marrow transplantation based on our clinical experience. Furthermore, we introduced our methods of performing FISH using blood smear or G banding specimens.
ISSN:0047-1860