The relationship between leptin and lipids in atherosclerosis
This study aimed to examine the extent to which leptin, alone or in combination with other risk factors, may be an independent marker for myocardial infarction in a region with a high incidence of cardiovascular disease. Leptin levels were measured by the ELISA method, while plasma lipids and lipopr...
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Published in | Indian heart journal Vol. 54; no. 6; pp. 692 - 696 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
India
01.11.2002
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Subjects | |
Online Access | Get full text |
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Summary: | This study aimed to examine the extent to which leptin, alone or in combination with other risk factors, may be an independent marker for myocardial infarction in a region with a high incidence of cardiovascular disease.
Leptin levels were measured by the ELISA method, while plasma lipids and lipoproteins were measured by conventional methods. Leptin levels were significantly higher in the patient than in the control group. Serum total cholesterol, low-density lipoprotein, lipoprotein (a) and apolipoprotein B showed a significant correlation with leptin, while high-density lipoprotein showed an inverse relation.
Our results suggest that leptin may be one factor operating in the metabolic alteration taking place during myocardial infarction, and is a possible risk factor. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0019-4832 |