The relationship between leptin and lipids in atherosclerosis

This study aimed to examine the extent to which leptin, alone or in combination with other risk factors, may be an independent marker for myocardial infarction in a region with a high incidence of cardiovascular disease. Leptin levels were measured by the ELISA method, while plasma lipids and lipopr...

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Bibliographic Details
Published inIndian heart journal Vol. 54; no. 6; pp. 692 - 696
Main Authors Tamer, L, Ercan, B, Unlü, A, Sucu, N, Pekdemir, H, Eskandari, G, Atik, U
Format Journal Article
LanguageEnglish
Published India 01.11.2002
Subjects
Apolipoproteins - blood
Arteriosclerosis - blood
Enzyme-Linked Immunosorbent Assay
Humans
Leptin - blood
Lipids - blood
Lipoprotein(a) - blood
Myocardial Infarction - blood
Risk Factors
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Summary:This study aimed to examine the extent to which leptin, alone or in combination with other risk factors, may be an independent marker for myocardial infarction in a region with a high incidence of cardiovascular disease. Leptin levels were measured by the ELISA method, while plasma lipids and lipoproteins were measured by conventional methods. Leptin levels were significantly higher in the patient than in the control group. Serum total cholesterol, low-density lipoprotein, lipoprotein (a) and apolipoprotein B showed a significant correlation with leptin, while high-density lipoprotein showed an inverse relation. Our results suggest that leptin may be one factor operating in the metabolic alteration taking place during myocardial infarction, and is a possible risk factor.
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ISSN:0019-4832