A patient with stage IIIc ovarian cancer with massive ascites who was chemotherapy resistant showed complete response with intraperitoneal hyperthermic chemoperfusion

Intraperitoneal hyperthermic chemoperfusion (IHCP) was performed on a stage IIIc ovarian cancer patient with massive ascites who had been chemotherapy resistant. Complete response was observed after the treatment. A 59-year-old woman with advanced ovarian cancer complained of massive refractory asci...

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Bibliographic Details
Published inGan to kagaku ryoho Vol. 30; no. 11; p. 1726
Main Authors Kobayashi, Kokuriki, Fujimoto, Shigeru, Takahashi, Makoto, Mutou, Takaaki, Toyosawa, Tadashi, Ohtsuka, Yasuhiro, Ogasawara, Takeshi
Format Journal Article
LanguageJapanese
Published Japan 01.10.2003
Subjects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Ascitic Fluid - etiology
Ascitic Fluid - therapy
Cisplatin - administration & dosage
Cystadenocarcinoma, Serous - pathology
Cystadenocarcinoma, Serous - surgery
Cystadenocarcinoma, Serous - therapy
Drug Resistance, Neoplasm
Female
Fluorouracil - administration & dosage
Humans
Hyperthermia, Induced
Infusions, Parenteral
Middle Aged
Mitomycin - administration & dosage
Neoplasm Staging
Ovarian Neoplasms - pathology
Ovarian Neoplasms - surgery
Ovarian Neoplasms - therapy
Ovariectomy
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Summary:Intraperitoneal hyperthermic chemoperfusion (IHCP) was performed on a stage IIIc ovarian cancer patient with massive ascites who had been chemotherapy resistant. Complete response was observed after the treatment. A 59-year-old woman with advanced ovarian cancer complained of massive refractory ascites after 2 years' history of chemotherapy. The patient received IHCP combined with surgery to remove the primary tumors and omentum. Soon after the treatment, the massive ascites disappeared and CA125 level decreased to normal. The patient remained free of ascites for 14 months after the treatment.
ISSN:0385-0684