Hydroxylapatite implants with or without collagen in the zygomatic arch of rats. Histological study

The authors studied the behavior of calcium phosphate materials used as inlay implants into bone cavities prepared in the zygomatic arch of rats. Fifty male albino rats were divided into four groups as follows: group I-preparation of bone cavities which did not receive any implant material as contro...

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Published inBrazilian dental journal Vol. 12; no. 1; pp. 9 - 15
Main Authors Gabrielli, M A, Marcantonio Júnior, E, Góissis, G, Okamoto, T, Gabrielli, M F, Vieira, E H
Format Journal Article
LanguageEnglish
Published Brazil 2001
Subjects
Animals
Biocompatible Materials - therapeutic use
Bone Substitutes - therapeutic use
Collagen - therapeutic use
Connective Tissue - pathology
Dentistry
Durapatite - therapeutic use
Fibroblasts - pathology
Follow-Up Studies
Giant Cells - pathology
Lymphocytes - pathology
Macrophages - pathology
Male
Neutrophils - pathology
Osteoblasts - pathology
Osteogenesis - physiology
Rats
Rats, Wistar
Zygoma - pathology
Zygoma - surgery
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Summary:The authors studied the behavior of calcium phosphate materials used as inlay implants into bone cavities prepared in the zygomatic arch of rats. Fifty male albino rats were divided into four groups as follows: group I-preparation of bone cavities which did not receive any implant material as controls; group II-implants of Interpore 200; group III-implants of experimental hydroxylapatite; group IV-implants of experimental hydroxylapatite combined with collagen. The animals were sacrificed after 5, 15, 30, 60 and 120 days and the specimens were submitted to histological analysis. Results showed that the experimental hydroxylapatite used in group III presented better osteogenic properties compared to the other materials. All tested materials were biocompatible, although group IV presented a more intense inflammatory response.
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ISSN:0103-6440