Insulin resistance, parameters of carbohydrate metabolism, anthropometric parameters, interactions in diabetic patients

• Published in: Annales Universitatis Mariae Curie-Skłodowska. Sectio D, Medicina Vol. 57; no. 1; p. 314
• Main Authors: Szydłowski, Wojciech, Łopatyński, Jerzy
• Format: Journal Article
• Language: English
• Published: Poland 2002
• Subjects: Adult; Aged; Anthropometry; Blood Glucose - metabolism; Diabetes Mellitus - diagnosis; Diabetes Mellitus - drug therapy; Diabetes Mellitus - physiopathology; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - physiopathology; Female; Glucose Tolerance Test; Glycated Hemoglobin A - metabolism; Humans; Hypoglycemic Agents - therapeutic use; Insulin Resistance - physiology; Islets of Langerhans - physiopathology; Male; Middle Aged; Obesity; Poland; Predictive Value of Tests; Reference Values
• ISSN: 0066-2240

The aim of the study was to investigate relationships between insulin resistance index and basic parameters of carbohydrate metabolism and anthropometric values. We investigated patients with diabetes mellitus t.2 (n = 36) treated with oral hypoglycemic agents. The control group represented patients with normal glucose tolerance (n = 37). Both, the group with diabetes and control had similar values of anthropometric parameters. The insulin resistance index showed significant correlations with fasting plasma insulin and glucose concentrations and HbA1C level in both groups. In the group with normal glucose tolerance we showed significant correlations between insulin resistance index and anthropometric parameters (waist circumference, BMI, body weight, WHR). We did not find any significant relationships between insulin resistance and anthropometric parameters in the diabetic group.