Advances in modulation of mammalian sperm function by fertilization promoting peptide

Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss by modulation of the adenylyl cyclase (AC)/cAMP signal transduction pathway. This is a review aimed at analyzing the function of fertilization promoting peptide during this process. The po...

Full description

Saved in:
Bibliographic Details
Published inZhonghua yi xue yi chuan xue za zhi Vol. 20; no. 2; p. 151
Main Authors Ma, Yongxin, Zhang, Sizhong
Format Journal Article
LanguageChinese
Published China 01.04.2003
Subjects
Acrosome - drug effects
Adenylyl Cyclases - metabolism
Animals
Cyclic AMP - metabolism
Humans
Male
Pyrrolidonecarboxylic Acid - analogs & derivatives
Signal Transduction - drug effects
Spermatozoa - drug effects
Spermatozoa - physiology
Thyrotropin-Releasing Hormone - analogs & derivatives
Thyrotropin-Releasing Hormone - pharmacology
Online AccessGet more information

Cover

More Information
Summary:Both fertilization promoting peptide and adenosine stimulate capacitation but inhibit spontaneous acrosome loss by modulation of the adenylyl cyclase (AC)/cAMP signal transduction pathway. This is a review aimed at analyzing the function of fertilization promoting peptide during this process. The possible molecular basis is also discussed.
ISSN:1003-9406