The effect of the Melissa officinalis extract on immune response in mice

The effect of an extract from Melissa officinalis on immune response in mice was analysed using the cytotoxicity test in three dilutions (undiluted extract and extract diluted 10 and 100 times) and hemagglutination and rosette tests with various routes of administration (oral and subcutaneous). The...

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Bibliographic Details
Published inActa Poloniae pharmaceutica Vol. 60; no. 6; p. 467
Main Authors Drozd, Janina, Anuszewska, Elzbieta
Format Journal Article
LanguageEnglish
Published Poland 01.11.2003
Subjects
Adjuvants, Immunologic - isolation & purification
Adjuvants, Immunologic - pharmacology
Animals
Cytotoxicity Tests, Immunologic - methods
Female
Melissa - immunology
Mice
Mice, Inbred BALB C
Plant Extracts - isolation & purification
Plant Extracts - pharmacology
Plant Structures
T-Lymphocytes - drug effects
T-Lymphocytes - immunology
Thymus Gland - cytology
Thymus Gland - drug effects
Thymus Gland - immunology
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Summary:The effect of an extract from Melissa officinalis on immune response in mice was analysed using the cytotoxicity test in three dilutions (undiluted extract and extract diluted 10 and 100 times) and hemagglutination and rosette tests with various routes of administration (oral and subcutaneous). The immunostimulating activity of the extract was compared with that of a synthetic compound--levamisole, which influence on the immune system is well known. The present results confirm the effect of water extracts from leaves of Melissa on the immune system, in both humoral and cellular response.
ISSN:0001-6837