High-resolution CT findings of pulmonary atypical adenomatous hyperplasia of 5 mm or less in diameter

• Published in: Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica Vol. 63; no. 6; p. 311
• Main Authors: Ishikawa, Hiroyuki, Koizumi, Naoya, Naito, Makoto, Umezu, Hajime, Morita, Tetsurou, Nemoto, Takeo, Saito, Tomoo, Okuizumi, Mina, Sasai, Keisuke
• Format: Journal Article
• Language: Japanese
• Published: Japan 01.07.2003
• Subjects: Adenocarcinoma, Bronchiolo-Alveolar - diagnostic imaging; Adenocarcinoma, Bronchiolo-Alveolar - pathology; Adenomatosis, Pulmonary - diagnostic imaging; Adenomatosis, Pulmonary - pathology; Aged; Female; Humans; Hyperplasia - diagnostic imaging; Hyperplasia - pathology; Lung Neoplasms - diagnostic imaging; Lung Neoplasms - pathology; Male; Middle Aged; Precancerous Conditions - diagnostic imaging; Radiographic Image Enhancement; Tomography, X-Ray Computed
• ISSN: 0048-0428

To clarify the high-resolution CT(HRCT) findings of pulmonary atypical adenomatous hyperplasia (AAH) of 5 mm or less in diameter. We evaluated the HRCT findings of 43 histopathologically confirmed AAH of 5 mm or less in diameter in 7 patients who underwent lobectomy for pulmonary adenocarcinoma. For comparison, we also examined the HRCT findings of 13 bronchioloalveolar carcinomas (BAC) of the same size from these patients. We identified 36 of 43 AAH and all 13 BAC on HRCT performed with multidetector-row CT. Thirty-five AAH and 11 BAC showed ground-glass opacity without any high-attenuation component. Margins of 20 AAH were well defined, and 16 were ill defined. In BAC, 11 lesions demonstrated well-defined margins, with only 2 showing ill-defined margins. Most AAH lesions of 5 mm or less in diameter are identified as ground-glass opacity on HRCT. Detection of minute ground-glass opacity is important in locating AAH on HRCT.