Bell's palsy and herpesviruses

A growing body of evidence links reactivation of herpesviruses (primarily varicella zoster virus and herpes simplex virus type 1) with the development of a large proportion of cases of acute peripheral facial palsy, a syndrome commonly known by its eponym, Bell's palsy. This article reviews the...

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Bibliographic Details
Published inHerpes Vol. 9; no. 3; p. 70
Main Author Gilbert, Stan C
Format Journal Article
LanguageEnglish
Published England 01.12.2002
Subjects
Bell Palsy - complications
Bell Palsy - drug therapy
Bell Palsy - etiology
Herpesviridae - pathogenicity
Herpesviridae - physiology
Herpesviridae Infections - complications
Humans
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Summary:A growing body of evidence links reactivation of herpesviruses (primarily varicella zoster virus and herpes simplex virus type 1) with the development of a large proportion of cases of acute peripheral facial palsy, a syndrome commonly known by its eponym, Bell's palsy. This article reviews the definition and natural history of the disease, its underlying anatomy and pathophysiology, the data linking herpetic reactivation with development of signs and symptoms, and therapeutic trials utilizing antiviral therapy. In addition, it poses the question, would earlier intervention with antivirals make a larger impact on outcomes?
ISSN:0969-7667