Genetic analysis of Yersinia pestis strains isolated in China

The strains of Yersinia pestis isolated in different period and different natural foci in China were analyzed. Traditional and molecular biological methods were used. Rhamnose fermentation, rRNA gene copy number, nitrite reduction, and the glycerol fermentation were important characters for typing,...

Full description

Saved in:
Bibliographic Details
Published inZhōnghuá liúxíngbìng zázhì Vol. 24; no. 11; p. 1005
Main Authors Yu, Dong-zheng, Hai, Rong, Dong, Xing-qi, Li, Min, Xia, Lian-xu, Shi, Xian-ming, Wei, Jian-chun, Cui, Bai-zhong, Wang, Peng, Sun, Lian-zhi, Zhang, Zhi-kai, Hu, Yuan, Zhang, En-min
Format Journal Article
LanguageChinese
Published China 01.11.2003
Subjects
China
Databases, Genetic
Electrophoresis, Gel, Pulsed-Field
Genetic Drift
Geography
Mutation
Random Amplified Polymorphic DNA Technique
Yersinia pestis - classification
Yersinia pestis - genetics
Yersinia pestis - isolation & purification
China
Online AccessGet more information

Cover

More Information
Summary:The strains of Yersinia pestis isolated in different period and different natural foci in China were analyzed. Traditional and molecular biological methods were used. Rhamnose fermentation, rRNA gene copy number, nitrite reduction, and the glycerol fermentation were important characters for typing, and pulse field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD) profile could reflect the genetic distance between the strains. The strains could be divided into 15 genetic types by those 6 characters with each of them covered an isolated geographical territories. The characters of strains were described; the genetic relationship of different types, their evolution, and the forming and shift of plague natural foci were analyzed.
ISSN:0254-6450