A case of duodenal adenocarcinoma arising from the heterotopic pancreas

Heterotopic pancreas, defined as the presence of pancreatic tissue that lacks anatomic and vascular continuity with the pancreas proper, may be more likely to undergo malignant change. However, malignancy arising from heterotopic pancreas is rare. In Korea, only one case of adenocarcinoma arising fr...

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Published inThe Korean journal of gastroenterology Vol. 42; no. 2; pp. 164 - 167
Main Authors Nam, Joo Young, Lee, Sang In, Chung, Jun Pyo, Choi, Sung Ho, Lee, Dok Yong, Choi, Jae Phil, Lee, Jung Il, Lee, Se Joon, Lee, Kwan Sik, Kang, Jin Kyung, Choi, Seung Ho, Kim, Ki Whang, Lim, Beom Jin, Park, Chan Il
Format Journal Article
LanguageKorean
Published Korea (South) 01.08.2003
Subjects
Adenocarcinoma - diagnosis
Adenocarcinoma - etiology
Adenocarcinoma - pathology
Choristoma - complications
Choristoma - diagnosis
Choristoma - pathology
Duodenal Neoplasms - diagnosis
Duodenal Neoplasms - etiology
Duodenal Neoplasms - pathology
Humans
Male
Middle Aged
Pancreas - pathology
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Summary:Heterotopic pancreas, defined as the presence of pancreatic tissue that lacks anatomic and vascular continuity with the pancreas proper, may be more likely to undergo malignant change. However, malignancy arising from heterotopic pancreas is rare. In Korea, only one case of adenocarcinoma arising from a gastric heterotopic pancreas has been reported. Recently, we experienced a case of duodenal carcinoma arising from heterotopic pancreas in a 64-year-old man. Endoscopic biopsy of the stenotic duodenum was positive for adenocarcinoma, and he underwent a pancreaticoduodenectomy with subtotal gastrectomy. Histologic examination of the resected specimen satisfied the proposed conditions that are necessary to prove that a malignancy arose from heterotopic pancreas. Despite an adjuvant chemotherapy, he died 10 months after surgery. Herein, we report a case of duodenal adenocarcinoma arising from heterotopic pancreas with a review of the relevant literature.
Bibliography:ObjectType-Article-2
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ISSN:1598-9992