A multivariate analysis of lower urinary tract ageing and urinary symptoms: the role of fibrosis

An investigative trial including 72 patients who underwent open surgery for benign prostatic hypertrophy (BPH) induced urinary symptoms was carried out with the purpose to obtain a deeper insight in the pathophysiology of this clinical picture. Prostate weight, stroma to parenchyma ratio, bladder wa...

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Bibliographic Details
Published inArchivio italiano di urologia, andrologia Vol. 71; no. 5; p. 287
Main Authors Bercovich, E, Barabino, G, Pirozzi-Farina, F, Deriu, M
Format Journal Article
LanguageEnglish
Published Italy 01.12.1999
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Summary:An investigative trial including 72 patients who underwent open surgery for benign prostatic hypertrophy (BPH) induced urinary symptoms was carried out with the purpose to obtain a deeper insight in the pathophysiology of this clinical picture. Prostate weight, stroma to parenchyma ratio, bladder wall fibrosis, I-PSS score, residual urine and uroflow obtained from these patients were processed by statistical multivariate analysis. The results point out the pivotal impact of prostate and bladder wall fibrosis in conditioning biological and chronological ageing of the lower urinary tract and relative symptoms.
ISSN:1124-3562