Metabolic and stress responses of the body to trauma: produced by the laparoscopic and open cholecystectomy

Laparoscopic cholecystectomy is regarded as gold standard therapy for symptomatic gall stone disease. This study was done to compare the metabolic and stress responses between open and lapraroscopic cholecystectomy and to evaluate their significance in postoperative recovery. Thirty patients with sy...

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Bibliographic Details
Published inMymensingh medical journal : MMJ Vol. 13; no. 1; p. 48
Main Authors Haque, Z, Rahman, M, Siddique, M A, Roy, R K, Chowdhury, R A, Rahman, M M, Rabbi, M A
Format Journal Article
LanguageEnglish
Published Bangladesh 01.01.2004
Subjects
Adult
Blood Glucose - analysis
Blood Glucose - metabolism
C-Reactive Protein - analysis
C-Reactive Protein - metabolism
Cholecystectomy - adverse effects
Cholecystectomy - methods
Cholecystectomy, Laparoscopic - adverse effects
Cholecystolithiasis - surgery
Epinephrine - blood
Epinephrine - metabolism
Female
Humans
Hydrocortisone - blood
Hydrocortisone - metabolism
Male
Middle Aged
Norepinephrine - blood
Norepinephrine - metabolism
Pain, Postoperative - metabolism
Postoperative Complications - metabolism
Prospective Studies
Stress, Physiological - blood
Stress, Physiological - etiology
Stress, Physiological - metabolism
Wounds and Injuries - blood
Wounds and Injuries - etiology
Wounds and Injuries - metabolism
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Summary:Laparoscopic cholecystectomy is regarded as gold standard therapy for symptomatic gall stone disease. This study was done to compare the metabolic and stress responses between open and lapraroscopic cholecystectomy and to evaluate their significance in postoperative recovery. Thirty patients with symptomatic gall stone disease were treated with open and laparoscopic cholecystectomy on elective basis (14 versus 16). Three samples of blood were collected from each patient to investigate serum cortisol, adrenaline, nor-adrenaline, C-reactive protein and blood glucose level. The mean age of patients was 41.86+/-10.13 blood glucose and stress hormones (cortisol, adrenaline, nor adrenaline) and C-reactive protein all were found significantly raised in the postoperative period in open cholecystectomy than laparoscopic cholecystectomy group. The postoperative recovery was also prolonged in the open group. The obvious clinical advantages of laparoscopic cholecystectomy over open cholecystectomy is mainly because of less metabolic and stress response.
ISSN:1022-4742