Ventricular septal defect with severe pulmonary hypertension: the role of open biopsy in determination of operative indication: a case report

A 51-year-old man having ventricular septal defect with severe pulmonary hypertension is reported. Operative indication that is denied was finally decided by open lung biopsy. He had pulmonary arterial pressure of 120/42 (70) mmHg. The ratio of pulmonary to systemic systolic pressure was 0.91, the r...

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Published inKyobu geka. The Japanese journal of thoracic surgery Vol. 48; no. 13; p. 1126
Main Authors Watanabe, S, Matsumoto, K, Shinzato, K, Shimokawa, S, Toyohira, H, Taira, A, Yoshida, A
Format Journal Article
LanguageJapanese
Published Japan 01.12.1995
Subjects
Biopsy
Heart Septal Defects, Ventricular - complications
Heart Septal Defects, Ventricular - surgery
Humans
Hypertension, Pulmonary - etiology
Hypertension, Pulmonary - pathology
Lung - pathology
Male
Middle Aged
Prognosis
Pulmonary Artery - physiopathology
Vascular Resistance
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Summary:A 51-year-old man having ventricular septal defect with severe pulmonary hypertension is reported. Operative indication that is denied was finally decided by open lung biopsy. He had pulmonary arterial pressure of 120/42 (70) mmHg. The ratio of pulmonary to systemic systolic pressure was 0.91, the ratio Of pulmonary to systemic flow was 1.26, the ratio of pulmonary to systemic vascular resistance was 0.34, and pulmonary vascular resistance was 14.2 unit x m2. For the reason of difficulty, in determination of operative indication through hemodynamic study, he received open lung biopsy. Histological assessment from biopsy specimen revealed severe occlusive pulmonary vascular disease exhibiting grade IV on the Heath Edwards classification. Open lung biopsy occasionally be selected in case with difficult determination of operative indication in severe pulmonary hypertension is a useful tool.
ISSN:0021-5252