A case of B-cell non-Hodgkin's lymphoma with prominent splenomegaly and high serum titer of cold agglutinin

The case of 37-year-old male with non-Hodgkin's lymphoma with prominent splenomegaly is presented. The spleen that was removed for analysis had a weight of 2690 grams and a section inspection revealed multiple, whitish, small nodules that were disseminated throughout the entire spleen. It was m...

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Bibliographic Details
Published inGan no rinsho. Japan journal of cancer clinics Vol. 36; no. 5; p. 651
Main Authors Fujise, K, Yazawa, M, Hashimoto, N, Sujino, H, Yanagisawa, T, Kawase, H, Ishihara, F, Kameda, H, Kuraishi, S, Kobayashi, S
Format Journal Article
LanguageJapanese
Published Japan 01.04.1990
Subjects
Adult
Agglutinins - metabolism
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
B-Lymphocytes
Combined Modality Therapy
Cryoglobulins
Cyclophosphamide - administration & dosage
Doxorubicin - administration & dosage
Humans
Immunoglobulin kappa-Chains - metabolism
Immunoglobulin M - metabolism
Lymphoma, Non-Hodgkin - complications
Lymphoma, Non-Hodgkin - immunology
Lymphoma, Non-Hodgkin - therapy
Male
Prednisone - administration & dosage
Splenectomy
Splenomegaly - etiology
Vincristine - administration & dosage
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Summary:The case of 37-year-old male with non-Hodgkin's lymphoma with prominent splenomegaly is presented. The spleen that was removed for analysis had a weight of 2690 grams and a section inspection revealed multiple, whitish, small nodules that were disseminated throughout the entire spleen. It was microscopically demonstrated to be a B-Cell lymphoma of diffuse, medium-sized cells and an IgM.kappa Type. This case also was complicated by a high serum titer of cold agglutinin that was decreased by chemotherapy.
ISSN:0021-4949