A curative report of multiple organ dysfunction syndrome and disseminated intravascular coagulation due to methicillin-resistant Staphylococcus aureus caused mediastinitis after cardiac surgery

We experienced a curative case, who was a fifty nine-year old man suffered from multiple organ dysfunction syndrome (MODS) and disseminated intravascular coagulation (DIC) due to Methicillin-resistant Staphylococcus aureus (MRSA) caused-mediastinitis following cardiac surgery against atrial septal d...

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Bibliographic Details
Published inKyobu geka. The Japanese journal of thoracic surgery Vol. 50; no. 2; p. 150
Main Authors Gu, K, Nakayama, K, Saitoh, Y, Nosaka, S, Ooishi, T, Sasaki, T, Yamauchi, M
Format Journal Article
LanguageJapanese
Published Japan 01.02.1997
Subjects
Cardiac Surgical Procedures
Disseminated Intravascular Coagulation - etiology
Disseminated Intravascular Coagulation - therapy
Heart Septal Defects, Atrial - surgery
Humans
Male
Mediastinitis - microbiology
Mediastinitis - therapy
Methicillin Resistance
Middle Aged
Multiple Organ Failure - etiology
Multiple Organ Failure - therapy
Postoperative Complications - therapy
Staphylococcal Infections
Staphylococcus aureus
Systemic Inflammatory Response Syndrome - etiology
Therapeutic Irrigation
Tricuspid Valve Insufficiency - surgery
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Summary:We experienced a curative case, who was a fifty nine-year old man suffered from multiple organ dysfunction syndrome (MODS) and disseminated intravascular coagulation (DIC) due to Methicillin-resistant Staphylococcus aureus (MRSA) caused-mediastinitis following cardiac surgery against atrial septal defect (ASD) and tricuspid regurgitation. We successfully treated him with mediastinal irrigations by a large quantities of physiological saline containing 1% Povidone iodine (PI) and MRSA sensitive antibiotics as well as artificial supports such as plasma pheresis and hemodialysis against failure organs. It may be due to the prompt treatment with mediastinal irrigation and well timed dosage of sensitive antibiotics against the origin of sepsis that such a serious patient like this case could be recovered from MODS and DIC. In addition, it may be very effective to irrigate with 1% PI against MRSA-caused-mediastinitis.
ISSN:0021-5252