Dual use of silver for management of chronic bone infections and infected non-unions

Broad spectrum antibacterial effect of electrically generated silver ions has been fully established. Present work consists of clinical evaluation of beneficial antibacterial effect of silver ions liberated electrically with the help of locally manufactured power pack in 920 proved cases of chronic...

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Bibliographic Details
Published inJournal of the Indian Medical Association Vol. 94; no. 3; p. 91
Main Authors Nand, S, Sengar, G K, Jain, V K, Gupta, T D
Format Journal Article
LanguageEnglish
Published India 01.03.1996
Subjects
Adolescent
Adult
Bacterial Infections - complications
Bacterial Infections - drug therapy
Child
Child, Preschool
Chronic Disease
Combined Modality Therapy
Female
Follow-Up Studies
Fractures, Spontaneous - drug therapy
Fractures, Spontaneous - microbiology
Fractures, Ununited - drug therapy
Fractures, Ununited - microbiology
Humans
Infant
Iontophoresis - methods
Male
Osteomyelitis - complications
Osteomyelitis - drug therapy
Silver - therapeutic use
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Summary:Broad spectrum antibacterial effect of electrically generated silver ions has been fully established. Present work consists of clinical evaluation of beneficial antibacterial effect of silver ions liberated electrically with the help of locally manufactured power pack in 920 proved cases of chronic osteomyelitis with or without pathological fractures and septic non-unions. Wound debridement, silver iontophoresis, proper immobilisation and subsequent wound care yielded not only control of bone infections in 85% cases, but also produced healing of pathological fractures in 83% patients. Results remained unaffected by age or sex of patient, type of bone involved, duration of previous illness or type of previous treatment. Follow-up varied from 6 months to 10 years. This technique is likely to open a new chapter in treatment of chronic resistant bone infections and septic non-unions due to open fractures particularly in developing countries of the world.
ISSN:0019-5847