The therapeutic effects of aspoxicillin on various infectious diseases in children

Clinical application to ascertain the effects of aspoxicillin (ASPC), a new semisynthetic penicillin antibiotic, upon several infectious diseases of children was performed in 7 cases with pneumonia, 5 cases with acute bronchitis, each case with tonsillitis, enterocolitis, urinary tract infection and...

Full description

Saved in:
Bibliographic Details
Published inJapanese journal of antibiotics Vol. 38; no. 7; p. 1925
Main Authors Wakiguchi, H, Maeda, A, Ohara, Y, Tone, Y, Araki, K, Shiraishi, T, Ogura, H, Kitamura, I
Format Journal Article
LanguageJapanese
Published Japan 01.07.1985
Subjects
Adolescent
Amoxicillin - administration & dosage
Amoxicillin - adverse effects
Amoxicillin - analogs & derivatives
Amoxicillin - therapeutic use
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Child
Child, Preschool
Drug Evaluation
Female
Hematologic Tests
Humans
Infant
Infusions, Parenteral
Kidney Function Tests
Liver Function Tests
Male
Online AccessGet full text

Cover

More Information
Summary:Clinical application to ascertain the effects of aspoxicillin (ASPC), a new semisynthetic penicillin antibiotic, upon several infectious diseases of children was performed in 7 cases with pneumonia, 5 cases with acute bronchitis, each case with tonsillitis, enterocolitis, urinary tract infection and suspected sepsis. ASPC was injected by drip infusion and the dosage was 63-117 mg/kg/day in 3 and 4 times a day. Clinical efficacy obtained as "excellent" was in 7 cases, "good" in 8 cases "poor" in 1 case, and efficacy rate was 93.8%. From the bacteriological point of view, eliminated in each of H. influenzae, H. parainfluenzae, group A beta-Streptococcus and unchanged in a case of E. coli. There were transient thrombocytopenia in 2 cases and eosinophilia in 3 cases.
ISSN:0368-2781
DOI:10.11553/antibiotics1968b.38.1925