Difference in learning and retention by Albino-Swiss mice. Part 5. Effect of some antidepressants

According to the methods described earlier (1), the effect of some antidepressants on memory retention in "good" and "poor" learning mice was studied. The present study indicates that several antidepressants have different activity on memory retrieval of the two subtypes of anima...

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Bibliographic Details
Published inMethods and findings in experimental and clinical pharmacology Vol. 10; no. 7; p. 427
Main Authors Valzelli, L, Skorupska, M, Kozak, W, Banfi, L
Format Journal Article
LanguageEnglish
Published Spain 01.07.1988
Subjects
Animals
Antidepressive Agents - pharmacology
Avoidance Learning - drug effects
Behavior, Animal - drug effects
Male
Memory - drug effects
Mice
Retention (Psychology) - drug effects
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Summary:According to the methods described earlier (1), the effect of some antidepressants on memory retention in "good" and "poor" learning mice was studied. The present study indicates that several antidepressants have different activity on memory retrieval of the two subtypes of animals, which is directly responsible for the results here reported. In general terms, the data obtained show that, in addition to the classical antidepressant activity, some derivatives may exert a behavioral disinhibition.
ISSN:0379-0355