Recurrent respiratory papillomatosis

Recurrent respiratory papillomatosis is a disease characterized by the growth of wart-like neoplasms anywhere along the aerodigestive tract. The etiologic agent is the human papillomavirus, of which 90 subtypes have been described. The age distribution of those affected appears to be a bimodal curve...

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Bibliographic Details
Published inThe Journal of the Louisiana State Medical Society Vol. 150; no. 10; p. 456
Main Authors Murray, L N, Miller, R H
Format Journal Article
LanguageEnglish
Published United States 01.10.1998
Subjects
Adult
Child, Preschool
Humans
Papilloma - diagnosis
Papilloma - epidemiology
Papilloma - therapy
Papillomaviridae
Papillomavirus Infections - diagnosis
Papillomavirus Infections - epidemiology
Papillomavirus Infections - therapy
Respiratory Tract Neoplasms - diagnosis
Respiratory Tract Neoplasms - epidemiology
Respiratory Tract Neoplasms - therapy
Tumor Virus Infections - diagnosis
Tumor Virus Infections - epidemiology
Tumor Virus Infections - therapy
United States - epidemiology
United States
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Summary:Recurrent respiratory papillomatosis is a disease characterized by the growth of wart-like neoplasms anywhere along the aerodigestive tract. The etiologic agent is the human papillomavirus, of which 90 subtypes have been described. The age distribution of those affected appears to be a bimodal curve, with the first peak around 5 years of age and the second occurring in adults in the third decade of life. The mainstay of treatment is surgical resection to maintain an adequate airway; patients often require multiple surgeries. The epidemiology, pathogenesis, clinical features, and treatment options are discussed. Current evidence regarding prognosis and the multifactorial nature of pathogenesis are also reviewed.
ISSN:0024-6921