Magnetic resonance imaging of brainstem lesions in a case of neuro-Behçet disease

We reported a 28-year-old man with multiple lesions in the brainstem which were clearly identified and followed up with MRI. He had been treated for Behçet uveitis using cyclosporine and colchicine during the past 5 years, and he acutely presented with fever and headache, followed left hemiparesis,...

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Bibliographic Details
Published inNo To Shinkei Vol. 49; no. 3; p. 273
Main Authors Nomura, E, Izumi, Y, Yamashita, H, Kamei, H, Nakamura, S, Wakabayashi, C, Yamaguchi, S, Kajikawa, H, Shohge, K
Format Journal Article
LanguageJapanese
Published Japan 01.03.1997
Subjects
Adrenal Cortex Hormones - administration & dosage
Adult
Behcet Syndrome - drug therapy
Behcet Syndrome - pathology
Brain Stem - pathology
Gadolinium DTPA
Humans
Magnetic Resonance Imaging
Male
Organometallic Compounds
Pentetic Acid - analogs & derivatives
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Summary:We reported a 28-year-old man with multiple lesions in the brainstem which were clearly identified and followed up with MRI. He had been treated for Behçet uveitis using cyclosporine and colchicine during the past 5 years, and he acutely presented with fever and headache, followed left hemiparesis, dysarthria and dysphagia. MRI on admission revealed multiple lesions in the ventral pontine region which showed mixed-intensity on T1WI, high-intensity on T2WI and enhancement with Gd-DTPA. His clinical symptoms spontaneously and gradually improved, but more rapidly improved due to additional administration of corticosteroid. The lesions in the brainstem became smaller and finally rudimentary during two months after the onset of neurological symptoms.
ISSN:0006-8969