Soluble interleukin-2 receptor levels in patients with pulmonary tuberculosis

Utilizing an enzyme-linked immunosorbent assay, we detected markedly elevated serum levels of soluble interleukin-2 (IL-2) receptors in patients with untreated pulmonary tuberculosis. In these patients, we also found that serum levels of soluble IL-2 receptors were closely correlated with serum aden...

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Published inNihon Kyōbu Shikkan Gakkai zasshi Vol. 27; no. 1; pp. 25 - 28
Main Authors Ito, M, Kojiro, N, Moriwaki, Y, Nishiki, M, Shirasaka, T, Ishihara, H, Aitani, M, Nakatsuji, Y, Hirose, T, Okada, M
Format Journal Article
LanguageJapanese
Published Japan 01.01.1989
Subjects
Adult
Aged
Female
Humans
Immunity, Cellular
Male
Middle Aged
Receptors, Interleukin-2 - analysis
Solubility
Tuberculosis, Pulmonary - immunology
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Summary:Utilizing an enzyme-linked immunosorbent assay, we detected markedly elevated serum levels of soluble interleukin-2 (IL-2) receptors in patients with untreated pulmonary tuberculosis. In these patients, we also found that serum levels of soluble IL-2 receptors were closely correlated with serum adenosine deaminase levels (r = 0.869, p less than 0.001). Therefore, serum soluble IL-2 receptors appear to reflect the existence of active cell-mediated immunity in pulmonary tuberculosis and may prove to be a useful immunological marker for pulmonary tuberculosis.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0301-1542