Presence of antisperm antibodies in the serum of Sardinian adult people. II. Study on a selected infertile population in north Sardinia

Among many possible causes of infertility an immunological factor must be considered, in particular the presence of antibodies to spermatozoa in the serum. In previous researches we confirmed the presence of antisperm antibodies in the serum of healthy men of North Sardinia in percentage equal to 2....

Full description

Saved in:
Bibliographic Details
Published inBollettino della Societa italiana di biologia sperimentale Vol. 68; no. 11; p. 671
Main Authors Pirino, A, Succu, A, Montella, A
Format Journal Article
LanguageEnglish
Published Italy 01.11.1992
Subjects
Adult
Autoantibodies - blood
Autoantibodies - immunology
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Humans
Infertility, Male - epidemiology
Infertility, Male - immunology
Italy - epidemiology
Male
Middle Aged
Spermatozoa - immunology
Italy
Online AccessGet more information

Cover

More Information
Summary:Among many possible causes of infertility an immunological factor must be considered, in particular the presence of antibodies to spermatozoa in the serum. In previous researches we confirmed the presence of antisperm antibodies in the serum of healthy men of North Sardinia in percentage equal to 2.4% of the considered population. The aim of the present study is to evaluate the correlation between the presence of antisperm antibodies and infertility. The presence of antispermatozoal antibodies has been evaluated in the serum of 124 men (aged 25-50) affected by unexplained infertility utilizing the indirect immunofluorescence and ELISA methods. The presence of antisperm antibodies has been found equal to 19.3% of the tested sera. These results show that the incidence of antisperm antibodies is higher in the serum of male partners from infertile couples than in healthy subjects (P < 0.01), also in a relatively segregated and pure population like the one studied.
ISSN:0037-8771