Phosprenyl: a novel drug with antiviral and immunomodulatory activity

A novel antiviral drug with immunomodulatory activity (Phosprenyl) is presented. The main active ingredient of the preparation is polyprenyl phosphates. This medicine is highly efficient against a number of viruses, including HIV in vitro, and tick-borne encephalitis and rabies viruses in the experi...

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Bibliographic Details
Published inArchivum Immunologiae et Therapiae Experimentalis Vol. 44; no. 5-6; p. 395
Main Authors Danilov, L L, Maltsev, S D, Deyeva, A V, Narovlyansky, A N, Sanin, A V, Ozherelkov, S V, Pronin, A V
Format Journal Article
LanguageEnglish
Published Switzerland 1996
Subjects
Adjuvants, Immunologic - chemistry
Adjuvants, Immunologic - pharmacology
Adjuvants, Immunologic - therapeutic use
Animals
Antiviral Agents - chemistry
Antiviral Agents - pharmacology
Antiviral Agents - therapeutic use
Clinical Trials as Topic
Cricetinae
Distemper - drug therapy
Dog Diseases - drug therapy
Dogs
Dolichol Phosphates - physiology
Drug Evaluation, Preclinical
Enteritis - drug therapy
Enteritis - veterinary
Hepatitis, Viral, Animal - drug therapy
Mice
Molecular Structure
Parvoviridae Infections - drug therapy
Parvoviridae Infections - veterinary
Polyisoprenyl Phosphates - chemistry
Polyisoprenyl Phosphates - pharmacology
Polyisoprenyl Phosphates - therapeutic use
Rats
Virus Diseases - drug therapy
Virus Diseases - veterinary
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Summary:A novel antiviral drug with immunomodulatory activity (Phosprenyl) is presented. The main active ingredient of the preparation is polyprenyl phosphates. This medicine is highly efficient against a number of viruses, including HIV in vitro, and tick-borne encephalitis and rabies viruses in the experimental models in vivo. In veterinary practice Phosprenyl is now regarded as an effective therapeutic means for treatment of canine distemper, hepatitis, enteritis, etc.
ISSN:0004-069X