Evaluation of Fagara zanthoxyloides root extract in sickle cell anemia blood in vitro
An aqueous extract was prepared from roots of Fagara zanthoxyloides and examined for evidence of an antisickling effect in vitro. Addition of 25 mg/ml of the extract to fresh blood samples from sickle anemia subjects produced no change in the blood oxygen dissociation curves, and approximately equal...
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Published in | Lloydia Vol. 38; no. 5; p. 387 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.09.1975
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Subjects | |
Online Access | Get more information |
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Summary: | An aqueous extract was prepared from roots of Fagara zanthoxyloides and examined for evidence of an antisickling effect in vitro. Addition of 25 mg/ml of the extract to fresh blood samples from sickle anemia subjects produced no change in the blood oxygen dissociation curves, and approximately equal percentages of sickled cells were observed at comparable oxygen saturation levels in the presence or absence of the extract. These observations fail to confirm previous reports describing an antisickling effect of root extracts of Fagara zanthoxyloides. |
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ISSN: | 0024-5461 |