Results with collagen fleece coated with fibrin glue (TachoComb). A macroscopical and histological experimental study

Diffuse bleeding from parenchymatous organs at conventional surgery is eliminated with the usual methods coagulation tamponade or styches. We performed experimental series at 9 dogs. After resection of spleen, liver, pancreas and kidney, the bleeding surface was covered by collagen fleece coated wit...

Full description

Saved in:
Bibliographic Details
Published inActa chirurgica Hungarica Vol. 36; no. 1-4; p. 221
Main Authors Martis, G, Mikó, I, Szendröi, T, Kathy, S, Kovács, J, Hajdu, Z
Format Journal Article
LanguageEnglish
Published Hungary 1997
Subjects
Animals
Aprotinin - administration & dosage
Aprotinin - therapeutic use
Blood Loss, Surgical - prevention & control
Dogs
Drug Combinations
Fibrin Tissue Adhesive - administration & dosage
Fibrin Tissue Adhesive - therapeutic use
Fibrinogen - administration & dosage
Fibrinogen - therapeutic use
Follow-Up Studies
Hemostasis, Surgical - methods
Hemostatics - administration & dosage
Hemostatics - therapeutic use
Hepatectomy
Kidney - pathology
Laparotomy
Liver - pathology
Nephrectomy
Pancreas - pathology
Pancreatectomy
Reoperation
Spleen - pathology
Splenectomy
Suture Techniques
Thrombin - administration & dosage
Thrombin - therapeutic use
Tissue Adhesions - pathology
Tissue Adhesives - therapeutic use
Wound Healing
Online AccessGet more information

Cover

More Information
Summary:Diffuse bleeding from parenchymatous organs at conventional surgery is eliminated with the usual methods coagulation tamponade or styches. We performed experimental series at 9 dogs. After resection of spleen, liver, pancreas and kidney, the bleeding surface was covered by collagen fleece coated with fibrin glue (TachoComb). Postoperatively 7 days, 10 days, 14 days and 28 days we made a relaparotomy. Then the results were analyzed macroscopically and microscopically. In the abdominal cavity neither significant quantity of blood nor greater adhesions were detected. At all cases the fibrin glue was found on place were it was put before. Histologically a perfect wound healing experienced. The fibrin glue (TachoComb) using at diffuse parenchymatous organs' bleeding give a very good results when the wound area is at least 1 cm beyond the immediate wound margin and the fibrin glue is applied onto the wound and pressed on it for 4-5 minutes.
ISSN:0231-4614