Studies on the effect of organophosphorus pesticide phosalone on mouse immune system

The effect of an organophosphorus pesticide-phosalone on some parameters of humoral and cellular immunologic response in mice was investigated. Haematological and morphological examinations were made parallelly. It was found that immunotropic effect of phosalone was a reversible process.

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Bibliographic Details
Published inArchivum veterinarium Polonicum Vol. 34; no. 3-4; p. 221
Main Authors Kowalczyk-Bronisz, S H, Kotz, J, Bubak, B, Pregiel, M
Format Journal Article
LanguageEnglish
Published Poland 1994
Subjects
Adrenal Glands - drug effects
Adrenal Glands - pathology
Animals
Antibody Formation - drug effects
Body Weight - drug effects
Female
Graft vs Host Reaction - immunology
Hypersensitivity, Delayed
Immunity, Cellular - drug effects
Insecticides - toxicity
Interleukin-1 - biosynthesis
Lethal Dose 50
Leukocyte Count - drug effects
Lymph Nodes - drug effects
Lymph Nodes - pathology
Lymphocyte Transfusion
Macrophages, Peritoneal - drug effects
Macrophages, Peritoneal - immunology
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Organ Size - drug effects
Organothiophosphorus Compounds - toxicity
Rosette Formation
Spleen - drug effects
Spleen - pathology
Thymus Gland - drug effects
Thymus Gland - pathology
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Summary:The effect of an organophosphorus pesticide-phosalone on some parameters of humoral and cellular immunologic response in mice was investigated. Haematological and morphological examinations were made parallelly. It was found that immunotropic effect of phosalone was a reversible process.
ISSN:1230-5359