Theory and clinical application of functional MRI: 3D-functional brain mapping

Functional magnetic resonance imaging (fMRI) was performed using a clinical 1.5 T MR scanner. Normal volunteers and patients with several neurological disorders were studied with somatosensory stimulation using sponge at right hand and visual stimulation using checkerboard pattern. Both fMR images b...

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Bibliographic Details
Published inNihon rinshō Vol. 55; no. 7; p. 1660
Main Authors Tanaka, C, Fukunaga, M, Umeda, M, Ebisu, T
Format Journal Article
LanguageJapanese
Published Japan 01.07.1997
Subjects
Brain - anatomy & histology
Brain - pathology
Brain Diseases - diagnosis
Brain Mapping - methods
Echo-Planar Imaging - methods
Humans
Image Enhancement - methods
Photic Stimulation
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Summary:Functional magnetic resonance imaging (fMRI) was performed using a clinical 1.5 T MR scanner. Normal volunteers and patients with several neurological disorders were studied with somatosensory stimulation using sponge at right hand and visual stimulation using checkerboard pattern. Both fMR images by gradient echo echo planar imaging and three dimensional gradient echo images were studied. Reconstructed 3 dimensional functional brain mapping was superimposed on 3D anatomical images. Apparent signal increase was observed at contra lateral sensorimotor cortex and secondary sensory cortex with sponge stimulation. In the case of left homonymous hemianopia due to cerebral infarction, increasing signal was only observed surrounding left calcarine fissure by using stimulation of all visual field. In conclusion, fMRI and 3-D functional brain mapping has extremely high potentiality to examine pathophysiology of various neurological disorders.
ISSN:0047-1852