A multivariate analysis of en bloc extended radical mastectomy versus conventional radical mastectomy in operable breast cancer

We made clinical trials of en bloc extended radical mastectomy (EXT) of a new type in 118 patients from 1980 through 1985. Conventional radical mastectomies (RDL) were also performed in 105 patients from 1973 through 1985. A multivariate analysis was performed to compare the results of EXT and RDL....

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Bibliographic Details
Published inNihon Geka Gakkai zasshi Vol. 91; no. 7; p. 883
Main Authors Noguchi, M, Taniya, T, Koyasaki, N, Miyazaki, I
Format Journal Article
LanguageJapanese
Published Japan 01.07.1990
Subjects
Adult
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Female
Humans
Lymph Node Excision
Lymphatic Metastasis
Mastectomy, Radical - methods
Middle Aged
Multivariate Analysis
Prognosis
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Summary:We made clinical trials of en bloc extended radical mastectomy (EXT) of a new type in 118 patients from 1980 through 1985. Conventional radical mastectomies (RDL) were also performed in 105 patients from 1973 through 1985. A multivariate analysis was performed to compare the results of EXT and RDL. As the result, the 5-year survival rates of 91 +/- 2.6% and 83 +/- 3.7% were achieved for the EXT and RDL groups, respectively (Cox P value for comparison of survival curves = 0.16). Adjusted Cox regression analysis revealed a significantly favorable result of EXT (P = 0.03). This difference was most remarkable in patients with one to three metastatic axillary lymph nodes, although it was not statistically significant because of too small number of patients available (P = 0.18). The results are thus not definite, but suggest that EXT may be advantageous over RDL especially in patients with a few metastatic axillary lymph nodes.
ISSN:0301-4894