Treatment of duodenal stress ulcer by means of chemical sclerosis of the gastric mucosa induced with a 60 percent glucose solution (results after 1--5 years)

• Published in: Revista de chirurgie, oncologie, radiologie, o.r.l., oftalmologie, stomatologie. Chirurgie Vol. 28; no. 4; p. 269
• Main Authors: Mandache, F, Prodescu, V, Constantinescu, S, Mateescu, D, Creţulescu, G, Poenaru, A, Gherguţ, A, Abramescu, N, Dimitriu, C, Popescu, M, Pahomeanu, M, Oprescu, S
• Format: Journal Article
• Language: English; Romanian
• Published: Romania 01.07.1979
• Subjects: Adult; Duodenal Ulcer - drug therapy; Duodenal Ulcer - etiology; Female; Gastric Mucosa - drug effects; Glucose - pharmacology; Glucose - therapeutic use; Humans; Male; Middle Aged; Sclerosis; Stress, Psychological - complications
• ISSN: 0377-5003

Sclerosing of the gastric mucosa with a 60% fresh sterile solution of glucose was applied in 60 selected patients with chronic conflictual duodenal ulcers, hyperacidic gastritis by vagal neurogenic hyper-reactivity, associated with ischaemic gastropathy developed on an sympathico-adrenergic background. The immediate operatory results were good. The late results (between 1 and 5 years) were as follows: the clinical, radiological and metabolic results were good in 57 patients. Gastric chemical analysis, the values of the hourly basal output remained high in 16,6% of the patients, and those of acidity stimulated by histamine administration remained high in 13,3% of the patients. No peptic recidive was recorded. Unsatisfactory late results were noted in 3 patients (of which forced indication of the method in one patient and non-association of drainage in two patients).