Urea and ammonia excretion into gastric juice in regularly dialyzed patients and patients after renal transplantation. I. Dialyzed patients

In regularly dialyzed patients in basal gastric juice and after stimulation with pentagastrin the volume of titrable acidity, urea and ammonia were assessed. It was revealed that in relation to the plasma urea concentration in basal juice the mean urea and ammonia concentration is roughly half and i...

Full description

Saved in:
Bibliographic Details
Published inCzechoslovak medicine Vol. 1; no. 3; p. 180
Main Authors Skála, I, Marecková, O, Růzicková, J, Bláha, J, Straková, M, Reneltová, I, Jirka, J, Kocandrle, V, Zvolánková, K
Format Journal Article
LanguageEnglish
Published Czech Republic 1978
Subjects
Ammonia - secretion
Gastric Juice - analysis
Humans
Kidney Transplantation
Renal Dialysis
Secretory Rate
Urea - blood
Urea - secretion
Online AccessGet more information

Cover

More Information
Summary:In regularly dialyzed patients in basal gastric juice and after stimulation with pentagastrin the volume of titrable acidity, urea and ammonia were assessed. It was revealed that in relation to the plasma urea concentration in basal juice the mean urea and ammonia concentration is roughly half and in stimulation juice roughly one third. The urea concentration in gastric juice is negatively correlated to the ammonia concentration. Urea excretion into the stomach depends on the plasma urea level and on the secretory gastric activity. The decisive factor of gastric secretion is probably parietal cell secretion. From the results ensues that gastric juice of dialyzed patients contains a quantitatively significant amount of urea and ammonia. Ammonia due to its neutralizing action distorts the examination of gastric acidity assessed by titration. The findings call for a revision of hitherto known data concerning gastric secretion of uraemic patients.
ISSN:0139-9179