ANTIBIOGRAM OF PATHOGENIC BACTERIA ISOLATED FROM PRE- AND POST-SURGERY VESICOVAGINAL FISTULA (VVF) PATIENTS IN ABAKALIKI, EBONYI STATE

• Published in: International journal of pharmaceutical sciences and research Vol. 7; no. 3; p. 1005
• Main Authors: Iroha, I R, Okafor-Alu, F N, Ugbo, E N, Ejikeugwu, C P, Nwuzo, A C, Nwakeze, A E, Moses, I B, Egwu, E, Nwibo, G N
• Format: Journal Article
• Language: English
• Published: 01.03.2016
• Subjects: Escherichia coli; Klebsiella pneumoniae; Staphylococcus aureus
• ISSN: 0975-8232
• DOI: 10.13040/IJPSR.0975-8232.7(3).1005-11

Vesicovaginal fistula (VVF) is an abnormal fistulous tract that extends between the bladder and the vagina - thus allowing the continuous involuntary discharge of urine into the vaginal vault of the affected patient. This study evaluated presumptively the prevalence and antibiogram of pathogenic bacteria isolated from pre- and post-surgery VVF patients. Urine samples were collected in duplicates from the VVF patients; and these were bacteriologically analyzed, using cysteine lactose electrolyte deficient (CLED) agar, MacConkey agar and blood agar. Susceptibility studies were carried out on the isolated pathogens using the disk diffusion method. Klebsiella pneumoniae, Escherichia coli, S. pyogenes and S. aureus were the most isolated bacteria from the urine samples of pre- and post-surgery VVF patients. The organisms showed highest levels of resistance to ceftazidime, cotrimoxazole, amoxicillin, nitrofurantoin, cefuroxime, amoxicillin-clavulanic acid and tetracycline. With the exception of some S. aureus isolates, all the organisms including K. pneumoniae, E. coli and S. aureus were completely resistant to imipenem.