SEPARATION AND CHARACTERIZATION OF TRITERPENE COMPOUND EUPHOL FROM THE LEAVES OF AZIMA TETRACANTHA

• Published in: International journal of pharmaceutical sciences and research Vol. 7; no. 8; p. 3423
• Main Authors: Kavitha, C, Sandhiya, V
• Format: Journal Article
• Language: English
• Published: 01.08.2016
• Subjects: Salvadoraceae
• ISSN: 0975-8232
• DOI: 10.13040/IJPSR.0975-8232.7(7).3423-27

Azima tetracantha is a small flowering shrub belongs to salvadoraceae family and commonly known as mulluchangu or mulsangu in Tamil. It is an best known medicinal plant ,which have a central role in the treatment of disease from pre historical period .From the plant lot of phytochemicals has been reported such as alkaloids, steroids ,tannins, terpenoids, flavonoids, glycosides, phenols etc and also possesses activities such as antioxidant, antifungal, antibacterial , hepatoprotective, antidiabetic and antihyperlipidemic etc .In the present study preliminary evaluation and isolation of an active pharmacological compound euphol was obtained from the chloroform extract of the leaves of Azima tetracantha was carried out. The compound euphol is a tetracyclic triterpene alcohol which produces antinociceptive effects in inflammatory and neuropathic pain. The compound was isolated by column chromatography and characterized by chemical test, TLC, FTIR, NMR, C 13 NMR spectrum. In future it may be a promising molecule for the management of neuropathic pain.